Piperidine → HCID 178523006, compound

HRID 1937874Notes

Reaction equation

HRID 1937874 reaction equation
C1CCNCC1.O=C(NCc1ccc(F)cc1)c1nc(Br)c2cccnc2c1O>C=CCc1ccccc1.CC(C)(C)[O-].CC(C)c1cccc(C(C)C)c1-n1ccn(-c2c(C(C)C)cccc2C(C)C)[c]1=[Pd][Cl].COCCOC.[K+]>O=C(NCc1ccc(F)cc1)c1nc(N2CCCCC2)c2cccnc2c1O

Participants

6

Reactant 2

HCID 8082PiperidineHCID 223464015-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide

Product 1

HCID 178523006HCID 178523006, compoundYield 90%

Reagents, catalysts & solvents 3

HCID 23665647Potassium tert-butoxideReagentHCID 178438929HCID 178438929, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-b662e17cdb1644bf8139f006b93a7938
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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