Piperidine → HCID 178426457, compound

HRID 1937875Notes

Reaction equation

HRID 1937875 reaction equation
C1CCNCC1.Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1Br>C=CCc1ccccc1.CC(C)(C)[O-].CC(C)c1cccc(C(C)C)c1-n1ccn(-c2c(C(C)C)cccc2C(C)C)[c]1=[Pd][Cl].COCCOC.[K+]>Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1N1CCCCC1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 193962Etravirine

Product 1

HCID 178426457HCID 178426457, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23665647Potassium tert-butoxideReagentHCID 178438929HCID 178438929, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-fd0d709ecabc4d6db9eff93bd5c06dab
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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