Piperidine → HCID 178439936, compound

HRID 1937879Notes

Reaction equation

HRID 1937879 reaction equation
C1CCNCC1.CCCc1nc2ccc(I)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1>C=CCc1ccccc1.CC(C)(C)[O-].CC(C)c1cccc(C(C)C)c1-n1ccn(-c2c(C(C)C)cccc2C(C)C)[c]1=[Pd][Cl].COCCOC.[K+]>CCCc1nc2ccc(N3CCCCC3)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 132556033HCID 132556033, compound

Product 1

HCID 178439936HCID 178439936, compoundYield 45%

Reagents, catalysts & solvents 3

HCID 23665647Potassium tert-butoxideReagentHCID 178438929HCID 178438929, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-7da26bc96b384e1ba6efbd4127df845d
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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