Piperidine → HCID 138973475, compound

HRID 1937881Notes

Reaction equation

HRID 1937881 reaction equation
C1CCNCC1.O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1>C=CCc1ccccc1.CC(C)(C)[O-].CC(C)c1cccc(C(C)C)c1-n1ccn(-c2c(C(C)C)cccc2C(C)C)[c]1=[Pd][Cl].COCCOC.[K+]>O=C1Nc2ccc(N3CCCCC3)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 64139Efavirenz

Product 1

HCID 138973475HCID 138973475, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23665647Potassium tert-butoxideReagentHCID 178438929HCID 178438929, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-8eec25cd28f3430eadba2483d406db23
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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