Piperidine → HCID 138973475, compound

HRID 1937935Notes

Reaction equation

HRID 1937935 reaction equation
C1CCNCC1.O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1>C1COCCO1.CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.Nc1ccccc1-c1[c-]cccc1.O=C([O-])[O-].[Cl][Pd+].[Cs+].[Cs+]>O=C1Nc2ccc(N3CCCCC3)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 64139Efavirenz

Product 1

HCID 138973475HCID 138973475, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 10796Cesium carbonateReagentHCID 771465301375325-68-0CatalystHCID 312751,4-DioxaneSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-ca0fe0d67b8b4360829bff140753e596
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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