Piperidine → HCID 178525540, compound

HRID 1937943Notes

Reaction equation

HRID 1937943 reaction equation
C1CCNCC1.O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21>CC(C)c1cc(C(C)C)c(-c2ccccc2P(C(C)(C)C)C(C)(C)C)c(C(C)C)c1.CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.CS(=O)(=O)O.CS(C)=O.Nc1ccccc1-c1[c-]cccc1.[Pd]>O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(N3CCCCC3)cc(F)cc21

Participants

6

Reactant 2

HCID 8082PiperidineHCID 11597294(R)-2-(5-broMo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Product 1

HCID 178525540HCID 178525540, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 90645613(2'-Amino-2-biphenylyl)palladium(1+) methanesulfonate-bis(2-methyl-2-propanyl)(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1:1)CatalystHCID 679Dimethyl SulfoxideSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-3297a667fc334d4382f8d80876d72e7f
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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