Piperidine → HCID 138973475, compound

HRID 1937953Notes

Reaction equation

HRID 1937953 reaction equation
C1CCNCC1.O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1>CC(C)c1cc(C(C)C)c(-c2ccccc2P(C(C)(C)C)C(C)(C)C)c(C(C)C)c1.CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.CS(=O)(=O)O.CS(C)=O.Nc1ccccc1-c1[c-]cccc1.[Pd]>O=C1Nc2ccc(N3CCCCC3)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 64139Efavirenz

Product 1

HCID 138973475HCID 138973475, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 90645613(2'-Amino-2-biphenylyl)palladium(1+) methanesulfonate-bis(2-methyl-2-propanyl)(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1:1)CatalystHCID 679Dimethyl SulfoxideSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-b55960a7831a47a088d50c2dad5c4f3c
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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