Piperidine → HCID 178499397, compound

HRID 1937955Notes

Reaction equation

HRID 1937955 reaction equation
C1CCNCC1.COC(=O)CC1CCc2cc(Br)cc3[nH]c(=O)c(=O)n1c23>CC(C)c1cc(C(C)C)c(-c2ccccc2P(C(C)(C)C)C(C)(C)C)c(C(C)C)c1.CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.CS(=O)(=O)O.CS(C)=O.Nc1ccccc1-c1[c-]cccc1.[Pd]>COC(=O)CC1CCc2cc(N3CCCCC3)cc3[nH]c(=O)c(=O)n1c23

Participants

6

Reactant 2

HCID 8082PiperidineHCID 10066635Methyl 2-(9-bromo-2,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[1,2,3-de]quinoxalin-5-yl)acetate

Product 1

HCID 178499397HCID 178499397, compoundYield 16%

Reagents, catalysts & solvents 3

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 90645613(2'-Amino-2-biphenylyl)palladium(1+) methanesulfonate-bis(2-methyl-2-propanyl)(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1:1)CatalystHCID 679Dimethyl SulfoxideSolvent2×

Conditions

Temperature
60 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-4b1d38030c6349eab72c0b04567666f5
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

Loading…