Piperidine → HCID 178470271, compound

HRID 1937956Notes

Reaction equation

HRID 1937956 reaction equation
C1CCNCC1.CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(Br)ccc1-2>CC(C)c1cc(C(C)C)c(-c2ccccc2P(C(C)(C)C)C(C)(C)C)c(C(C)C)c1.CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.CS(=O)(=O)O.CS(C)=O.Nc1ccccc1-c1[c-]cccc1.[Pd]>CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(N3CCCCC3)ccc1-2

Participants

6

Reactant 2

HCID 8082PiperidineHCID 10737466Ethyl 8-bromo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate

Product 1

HCID 178470271HCID 178470271, compoundYield 46%

Reagents, catalysts & solvents 3

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 90645613(2'-Amino-2-biphenylyl)palladium(1+) methanesulfonate-bis(2-methyl-2-propanyl)(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1:1)CatalystHCID 679Dimethyl SulfoxideSolvent2×

Conditions

Temperature
60 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-c3c9d3d92fa143a0a725b4ec5f19158e
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

Loading…