Piperidine → HCID 178481514, compound

HRID 1937967Notes

Reaction equation

HRID 1937967 reaction equation
C1CCNCC1.CN1C(=O)C[C@@](C)(c2cc(Br)cs2)N/C1=N/C(=O)OC(C)(C)C>CC(C)c1cc(C(C)C)c(-c2ccccc2P(C(C)(C)C)C(C)(C)C)c(C(C)C)c1.CCN=P(N=P(N(C)C)(N(C)C)N(C)C)(N(C)C)N(C)C.CS(=O)(=O)O.CS(C)=O.Nc1ccccc1-c1[c-]cccc1.[Pd]>CN1C(=O)C[C@@](C)(c2cc(N3CCCCC3)cs2)N/C1=N/C(=O)OC(C)(C)C

Participants

6

Reactant 2

HCID 8082PiperidineHCID 178481496HCID 178481496, compound

Product 1

HCID 178481514HCID 178481514, compoundYield 4%

Reagents, catalysts & solvents 3

HCID 33931062,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineReagentHCID 90645613(2'-Amino-2-biphenylyl)palladium(1+) methanesulfonate-bis(2-methyl-2-propanyl)(2',4',6'-triisopropyl-2-biphenylyl)phosphine (1:1:1)CatalystHCID 679Dimethyl SulfoxideSolvent2×

Conditions

Temperature
60 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-6cf76951531e4d4f8b9474b167a00277
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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