6-Bromoindole → HCID 178480025, compound

HRID 1937975Notes

Reaction equation

HRID 1937975 reaction equation
Brc1ccc2cc[nH]c2c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)c2ccccc21>COCCOC.O.O=C([O-])[O-].[Na+].[Na+].[Pd].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>Cn1cc(-c2ccc3cc[nH]c3c2)c2ccccc21

Participants

8

Reactant 2

HCID 6764936-BromoindoleHCID 230580031-methyl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Product 1

HCID 178480025HCID 178480025, compoundYield 89%

Reagents, catalysts & solvents 5

HCID 10340Sodium CarbonateReagentHCID 11979704Tetrakis(triphenylphosphine)palladiumCatalystHCID 962WaterSolventHCID 80711,2-DimethoxyethaneSolvent2×HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
85 °C

Workup

  1. stirringNo procedure recorded

Sources & evidence

ORD record
ord-50aec05439e14b52b85436a835e178c8
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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