6-Bromoindole → HCID 178420860, compound

HRID 1937997Notes

Reaction equation

HRID 1937997 reaction equation
Brc1ccc2cc[nH]c2c1.CC1(C)OB(c2ccc3ncnn3c2)OC1(C)C>COCCOC.O.O=C([O-])[O-].[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[Cl][Pd][Cl].[Fe].[Na+].[Na+]>c1nc2ccc(-c3ccc4cc[nH]c4c3)cn2n1

Participants

8

Reactant 2

HCID 6764936-BromoindoleHCID 584463746-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-[1,2,4]triazolo[1,5-a]pyridine

Product 1

HCID 178420860HCID 178420860, compoundYield 48%

Reagents, catalysts & solvents 5

HCID 10340Sodium CarbonateReagentHCID 178477754HCID 178477754, compoundCatalystHCID 962WaterSolventHCID 80711,2-DimethoxyethaneSolvent2×HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
85 °C

Workup

  1. stirringNo procedure recorded

Sources & evidence

ORD record
ord-9af4283fc9bb4614b97d25ca16c52cf4
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

Loading…