6-Bromoindole → HCID 178419987, compound

HRID 1938002Notes

Reaction equation

HRID 1938002 reaction equation
Brc1ccc2cc[nH]c2c1.CC1(C)OB(c2cnc3ccccc3c2)OC1(C)C>COCCOC.O.O=C([O-])[O-].[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[Cl][Pd][Cl].[Fe].[Na+].[Na+]>c1ccc2ncc(-c3ccc4cc[nH]c4c3)cc2c1

Participants

8

Reactant 2

HCID 6764936-BromoindoleHCID 108485903-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline

Product 1

HCID 178419987HCID 178419987, compoundYield 82%

Reagents, catalysts & solvents 5

HCID 10340Sodium CarbonateReagentHCID 178477754HCID 178477754, compoundCatalystHCID 962WaterSolventHCID 80711,2-DimethoxyethaneSolvent2×HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
85 °C

Workup

  1. stirringNo procedure recorded

Sources & evidence

ORD record
ord-34855029e9b148aabbf96bc4e3f09553
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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