6-Bromoindole → HCID 178420769, compound

HRID 1938009Notes

Reaction equation

HRID 1938009 reaction equation
Brc1ccc2cc[nH]c2c1.CC1(C)OB(c2ccc(-c3cccnc3)nc2)OC1(C)C>COCCOC.O.O=C([O-])[O-].[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[CH]1[CH][CH]C(P(c2ccccc2)c2ccccc2)[CH]1.[Cl][Pd][Cl].[Fe].[Na+].[Na+]>c1cncc(-c2ccc(-c3ccc4cc[nH]c4c3)cn2)c1

Participants

8

Reactant 2

HCID 6764936-BromoindoleHCID 45786528HCID 45786528, compound

Product 1

HCID 178420769HCID 178420769, compoundYield 62%

Reagents, catalysts & solvents 5

HCID 10340Sodium CarbonateReagentHCID 178477754HCID 178477754, compoundCatalystHCID 962WaterSolventHCID 80711,2-DimethoxyethaneSolvent2×HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
85 °C

Workup

  1. stirringNo procedure recorded

Sources & evidence

ORD record
ord-56e9e602849444408f397dbca8597bc3
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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