反应详情

Using a procedure similar to that described in Example 11, but substituting 1-[4-(N,N-diethylaminosulfonyl)phenyl]-4,4,4-trifluoro-3-hydroxy-3-methylbut-1-yne for the 4,4,4-trifluoro-3-hydroxy-3-methyl-1-[4-(1-pyrrolidinylsulfonyl)phenyl]but-1-yne used therein, the title compound was prepared; mp 112.1°-117.2° C.; MS: m/z=352(M+1). Analysis for C15 H20F3NO3S: Calculated: C, 51.27; H, 5.74; N, 3.99. Found: C, 51.17; H, 5.96; N, 3.87.