3-Nitro-7-(2-trifluoromethylbenzyloxy)quinoline → 3-Amino-7-(2-trifluoromethylbenzyloxy)quinoline

Participants

Reaction Steps

In ethanol (30 mL) was suspended 3-nitro-7-(2-trifluoromethylbenzyloxy)quinoline (600 mg, 1.72 mmol.), and to the suspension was added platinum oxide (72 mg). Then, catalytic reduction was performed for 3 hours. After the completion of reaction was confirmed, the reaction mixture was filtered over Celite®, and the filtrate was placed under reduced pressure to leave the desired compound as brown oil in the quantitative yield.

Provenance & Evidence