Hydrochloric Acid → 3-Methyl-2-furoic acid

HRID 1938853Notes

Reaction equation

HRID 1938853 reaction equation
[CH3:1][C:2]1[CH:6]=[CH:5][O:4][C:3]=1[C:7]([O:9]C)=[O:8].[OH-].[Na+].O.Cl>C(O)C>[CH3:1][C:2]1[CH:6]=[CH:5][O:4][C:3]=1[C:7]([OH:9])=[O:8]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 14798Sodium HydroxideHCID 350231Methyl 3-methyl-2-furoate

Product 1

HCID 781273-Methyl-2-furoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3-Methyl-2-furancarboxylic acid (41 g, m.p. 136°-138° C.) was prepared by refluxing methyl 3-methyl-2-furancarboxylate 54g, (Organic Synthesis, Coll. Vol. IV, p. 649), sodium hydroxide (20 g), water (100 ml) and ethanol (100 ml), then cooling and acidifying with concentrated hydrochloric acid.

Workup

  1. temperaturecooling

Sources & evidence

ORD record
ord-c4d3d72b38b8435491f4013aaa050265
Source dataset
uspto-grants-1997_12
Patent number
US05693827

Reaction notes

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