Thionyl Chloride → 3-Methylfuran-2-carbonyl chloride

HRID 1938854Notes

Reaction equation

HRID 1938854 reaction equation
[CH3:1][C:2]1[CH:6]=[CH:5][O:4][C:3]=1[C:7]([OH:9])=O.S(Cl)([Cl:12])=O>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:6]=[CH:5][O:4][C:3]=1[C:7]([Cl:12])=[O:9]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 781273-Methyl-2-furoic acid

Product 1

HCID 27966743-Methylfuran-2-carbonyl chloride

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

3-Methyl-2-furancarbonyl chloride was prepared by refluxing 3-methyl-2-furancarboxylic acid (20.0 g) with thionyl chloride (25 ml) in toluene (75 ml) for 3 hours. After removal of the solvent, the acid chloride was distilled (b.p. 74°-76° C. at ca. 12 mm).

Workup

  1. customAfter removal of the solvent
  2. distillationthe acid chloride was distilled (b.p. 74°-76° C. at ca. 12 mm)

Sources & evidence

ORD record
ord-f64822d702a043b690ce1a55d07162f8
Source dataset
uspto-grants-1997_12
Patent number
US05693827

Reaction notes

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