HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cysteamine Hydrochloride → HCID 131718855, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cysteamine Hydrochloride | HCID 9082 | — |
| Reactant | 3,4,4-Trifluoro-3-butenoyl chloride | HCID 10920789 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 131718855 | HCID 131718855 | 34% |
Reaction Steps
A mixture of 3,4,4-trifluoro-3-butenoyl chloride (2.5 g, 0.0158 mole) and 2-aminoethanethiol hydrochloride (1.14 g, 0.010 mole) is slowly heated to reflux for 15 min. The mixture is cooled to room temperature and treated with dry ether and filtered. The product is recrystallized from absolute ethanol to give 0.8 g of the title compound as a off-white solid, a 34% yield. m.p. 95°-115° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05693865 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-a1a3d5569b8a4198b671a31576eb2ba6 |
| Source note | uspto-grants-1997_12 |