HCID 22870621, compound → HCID 22870622, compound

HRID 1938932Notes

Reaction equation

HRID 1938932 reaction equation
[C:1]([CH2:11][CH2:12][C:13]([O:15][CH:16]([C@@H:18]1[C@:35]2([CH3:36])[C@H:21]([C@H:22]3[C@H:32]([CH2:33][CH2:34]2)[C@:30]2([CH3:31])[C@H:25]([N:26]([CH3:38])[C:27](=[O:37])[CH2:28][CH2:29]2)[CH2:24][CH2:23]3)[CH2:20][CH2:19]1)[CH3:17])=[O:14])([O:3]CC1C=CC=CC=1)=[O:2].[H][H]>C(OCC)(=O)C.[Pd]>[C:1]([CH2:11][CH2:12][C:13]([O:15][CH:16]([C@@H:18]1[C@:35]2([CH3:36])[C@H:21]([C@H:22]3[C@H:32]([CH2:33][CH2:34]2)[C@:30]2([CH3:31])[C@H:25]([N:26]([CH3:38])[C:27](=[O:37])[CH2:28][CH2:29]2)[CH2:24][CH2:23]3)[CH2:20][CH2:19]1)[CH3:17])=[O:14])([OH:3])=[O:2]

Participants

5

Reactant 2

HCID 22870621HCID 22870621, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22870622HCID 22870622, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

20-(3-(Carbobenzyloxy)propionyloxy)-4-methyl-5a-4-azapregnan-3-one (0.05 g, 0.095 mM) was reduced with hydrogen in ethyl acetate in the presence of 5% palladium on carbon, to obtain the title compound. MS M+1 calculated for C25H39NO5, mw=433.64; observed m/e 434.

Sources & evidence

ORD record
ord-73ad1e158dd74b7680a547fb629c78cc
Source dataset
uspto-grants-1997_12
Patent number
US05693809

Reaction notes

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