Dichloromethane → 1-[2-(4-Aminopiperidin-1-yl)ethyl]-7-methoxy-1,4-dihydro-2H-3,1-benzoxazin-2-one
Reaction equation
[C:1]([N:5]([C:2](=[O:3])[O-:4])[CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]2[C:18](=[O:29])[O:19][CH2:20][c:21]3[c:22]2[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[CH2:13][CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH2:5][CH:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]2[C:18](=[O:29])[O:19][CH2:20][c:21]3[c:22]2[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]3)[CH2:13][CH2:14]1Participants
4
Sources & evidence
- ORD record
- ord-53c0def5072d4189976fe2c0834d6090
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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