HCID 15405501, compound → HCID 15405503, compound

HRID 1939140Notes

Reaction equation

HRID 1939140 reaction equation
[C:1]([O:4][CH2:5][C:6]1[O:11][C:10](C)(C)O[C:8](=[O:14])[C:7]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(=[O:3])[CH3:2].C=[N:22][C:23]([CH3:31])([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[CH3:24]>C1(C)C(C)=CC=CC=1>[C:1]([O:4][CH2:5][C:6]1[O:11][CH2:10][N:22]([C:23]([CH3:31])([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH3:24])[C:8](=[O:14])[C:7]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 15405501HCID 15405501, compoundHCID 15405502HCID 15405502, compound

Product 1

HCID 15405503HCID 15405503, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of 6-acetyloxymethyl-2,2-dimethyl-5-phenyl-2H,4H-1,3-dioxin-4-one (Compound No. 241, 5.0 g) and N-methylene-1-methyl-1-phenylethylamine (2.9 g) was dissolved in xylene (40 ml) and allowed to react by refluxing for 30 minutes. The reaction mixture was purified by silica gel chromatography to afford the captioned compound (yield 72%).

Workup

  1. customto react
  2. temperatureby refluxing for 30 minutes
  3. customThe reaction mixture was purified by silica gel chromatography

Sources & evidence

ORD record
ord-5d90052afe2f4e23acdf7f75bee9208b
Source dataset
uspto-grants-1997_12
Patent number
US05696054

Reaction notes

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