Hydroxyamine hydrochloride → HCID 86751702, compound

Participants

Reaction Steps

6-Formyl-3-(1-methyl-1-phenylethyl)-5-phenyl-2,3-dihydro-4H-1,3-oxazin-4-one (Compound No. 121, 2.87 g) was dissolved in ethanol (30 ml), and an aqueous solution (15 ml) of hydroxylamine hydrochloric acid (0.65 g) and sodium acetate (1.30 g) was added slowly thereto at room temperature. After stirring for one hour, ethanol was removed by evaporation, and filtered after adding water. The solid product obtained was rinsed with water and dried to afford the captioned compound (2.59 g, yield 86%).

Provenance & Evidence