Water → HCID 11183541, compound

HRID 1939152Notes

Reaction equation

HRID 1939152 reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:3]=1[O:4][CH2:5][CH2:6][C:7]([OH:9])=O.O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O.O>CS(O)(=O)=O>[Cl:14][C:12]1[CH:13]=[C:2]([Cl:1])[C:3]2[O:4][CH2:5][CH2:6][C:7](=[O:9])[C:10]=2[CH:11]=1

Participants

5

Reactant 3

HCID 962WaterHCID 14812Phosphorus oxide (P4O10)HCID 1190483-(2,4-Dichlorophenoxy)propanoic acid

Product 1

HCID 11183541HCID 11183541, compoundYield 94.8%

Reagents, catalysts & solvents 1

HCID 6395Methanesulfonic AcidSolvent

Procedure

3-(2,4-Dichlorophenoxy)propionic acid (52.36 g, 0.223 mol) is added portion-wise to a mixture of phosphorus pentoxide (70.98 g, 0.490 mol) in methanesulfonic acid (Eatoh's reagent) under nitrogen. The reaction mixture is stirred at room temperature for 4 hours, poured into water and filtered to obtain a solid. The solid is washed with water and dried in a vacuum oven to give the title product as an off-white solid (45.88 g, mp 86°-87° C.).

Workup

  1. filtrationfiltered
  2. customto obtain a solid
  3. washThe solid is washed with water
  4. customdried in a vacuum oven

Sources & evidence

ORD record
ord-da7085717e3f436299f978a4c6f33dde
Source dataset
uspto-grants-1997_12
Patent number
US05696050

Reaction notes

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