反应详情

A mixture of 4-amino-3-nitrobenzoic acid (7.40 g), 1-hydroxybenzotriazole (6.59 g) , dicyclohexylcarbodiimide (10.90 g) , dry N,N-dimethylformamide (74 ml), and morpholine (4.3 ml) was stirred at room temperature for 2 hours. The insolubles were filtered out, and washed with N,N-dimethylformamide. The filtrate and the washing were combined, and concentrated to obtain a yellowish brown solid (16.01 g).

1. filtrationThe insolubles were filtered out
2. washwashed with N,N-dimethylformamide
3. concentrationconcentrated