HCID 18349474, compound → 4-Methoxyphenyl 5,6-dihydroxyhexyl ether

HRID 1939618Notes

Reaction equation

HRID 1939618 reaction equation
CC1(C)[O:6][CH:5]([CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH2:4][O:3]1>C(O)(=O)C>[OH:6][CH:5]([CH2:4][OH:3])[CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=1

Participants

3

Reactant 1

HCID 18349474HCID 18349474, compound

Product 1

HCID 183494674-Methoxyphenyl 5,6-dihydroxyhexyl ether

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2.08 g of 4-methoxyphenyl 4-(2,2-dimethyldioxolan-4-yl)butyl ether from Example 1b were dissolved in 165 ml of 80% acetic acid and stirred at room temperature for 4 h. The acetic acid was separated off in vacuo, and the mixture was then coevaporated with toluene/methanol twice. This resulted in a crystalline product.

Workup

  1. customThe acetic acid was separated off in vacuo
  2. customThis resulted in a crystalline product

Sources & evidence

ORD record
ord-4438c891a7934e9faa0e8f722004a4b4
Source dataset
uspto-grants-1997_12
Patent number
US05696248

Reaction notes

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