反应详情

A solution of (S)-4-(4-benzyloxy-benzyl)-2,2-dimethyl-[1,3]dioxolane (1.00 g, 3.35 mmol) in ethyl acetate (50 mL) was treated with 10% palladium on carbon (0.360 g, 0.34 mmol) and the resulting mixture hydrogenated under 1 atm of hydrogen pressure. The resulting mixture was filtered through a pad of Celite® and the pad of Celite washed with ethyl acetate. The filtrate was concentrated in vacuo to afford 4-((S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-phenol (696 mg, 100%).

1. filtrationThe resulting mixture was filtered through a pad of Celite®
2. washthe pad of Celite washed with ethyl acetate
3. concentrationThe filtrate was concentrated in vacuo