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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1939955Generated: November 2, 2026

1-Bromo-3-chloropropane → 4-[3-(4-Morpholinyl)propoxy]benzonitrile

https://huagongshe.com/reaction/1939955

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-chloropropaneHCID 8006—
ReactantMorpholineHCID 8083—
Reactant4-CyanophenolHCID 13019—
Product4-[3-(4-Morpholinyl)propoxy]benzonitrileHCID 2993836—

Reaction Steps

According to a similar manner as that in Reference Example 78 except that 4-cyanophenol, 1-bromo-3-chloropropane, and morpholine were used, 4-(3-morpholinopropoxy)benzonitrile (quantitative) was obtained as a crude product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05698560
Source datasetuspto-grants-1997_12
ORD IDord-03fc735140404d9084a0497c44ab91f8
Source noteuspto-grants-1997_12