Morpholine → HCID 2995544, compound

HRID 1939957Notes

Reaction equation

HRID 1939957 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1)#[N:2].Br[CH2:11][CH2:12][CH2:13][CH2:14]Cl.[NH:16]1[CH2:21][CH2:20][O:19][CH2:18][CH2:17]1>>[O:19]1[CH2:20][CH2:21][N:16]([CH2:11][CH2:12][CH2:13][CH2:14][O:9][C:6]2[CH:7]=[CH:8][C:3]([C:1]#[N:2])=[CH:4][CH:5]=2)[CH2:17][CH2:18]1

Participants

4

Reactant 3

HCID 8083MorpholineHCID 130194-CyanophenolHCID 813641-Bromo-4-chlorobutane

Product 1

HCID 2995544HCID 2995544, compoundYield 86%

Procedure

According to a similar manner as that in Reference Example 78 except that 4-cyanophenol, 1-bromo-4-chlorobutane, and morpholine were used, 4-(4-morpholinobutoxy)benzonitrile (86%) was obtained as a crude product.

Sources & evidence

ORD record
ord-841a7aeb3b2348edb067ff22f41c737a
Source dataset
uspto-grants-1997_12
Patent number
US05698560

Reaction notes

Loading…