HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → [[4-[[N-[3-(piperidin-4-yl)propionyl]-N-methylamino]acetyl]-o-phenylene]dioxy]diacetic acid trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Di-t-butyl[[4-[[N-[3-(1-t-butyloxycarbonylpiperidin-4-yl)propionyl]-N-methylamino]acetyl]-o-phenylene]dioxy]diacetate | HCID 21466012 | — |
| Product | [[4-[[N-[3-(piperidin-4-yl)propionyl]-N-methylamino]acetyl]-o-phenylene]dioxy]diacetic acid trifluoroacetate | HCID 67624455 | — |
Reaction Steps
The solution of 250 mg of the compound prepared in (a) in 2 ml of trifluoroacetic acid was stirred at room temperature for 3 hours. Afer the solvent was evaporated under reduced pressure, ether was added and deposited crystals were collected by filtration to give 168 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05698692 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-ecefebe87511418ebf5eae66ff8c7423 |
| Source note | uspto-grants-1997_12 |