HRID1940376

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CN(CC(=O)c1ccc(OC(C(=O)[O-])(C(C)(C)C)C(C)(C)C)c(OCC(=O)[O-])c1)C(=O)CCC1CCN(C(=O)OC(C)(C)C)CC1

HCID21466012

未命名化合物

PRODUCTS

生成物

结构：CN(CC(=O)c1ccc(OCC(=O)O)c(OCC(=O)O)c1)C(=O)CCC1CCNCC1.O=C(O)C(F)(F)F

HCID67624455

未命名化合物

PROCEDURE

实验过程

The solution of 250 mg of the compound prepared in (a) in 2 ml of trifluoroacetic acid was stirred at room temperature for 3 hours. Afer the solvent was evaporated under reduced pressure, ether was added and deposited crystals were collected by filtration to give 168 mg of the title compound.

WORKUP

后处理

customAfer the solvent was evaporated under reduced pressure, ether
additionwas added
filtrationwere collected by filtration

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ecefebe87511418ebf5eae66ff8c7423
来源数据集: uspto-grants-1997_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05698692
来源说明: uspto-grants-1997_12

反应 SMILES

C([C:5](C(C)(C)C)([O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16](=[O:37])[CH2:17][N:18]([C:20](=[O:36])[CH2:21][CH2:22][CH:23]2[CH2:28][CH2:27][N:26](C(OC(C)(C)C)=O)[CH2:25][CH2:24]2)[CH3:19])=[CH:12][C:11]=1[O:38][CH2:39][C:40]([O-:42])=[O:41])[C:6]([O-:8])=[O:7])(C)(C)C.[F:47][C:48]([F:53])([F:52])[C:49]([OH:51])=[O:50]>>[F:47][C:48]([F:53])([F:52])[C:49]([OH:51])=[O:50].[NH:26]1[CH2:27][CH2:28][CH:23]([CH2:22][CH2:21][C:20]([N:18]([CH2:17][C:16]([C:13]2[CH:14]=[CH:15][C:10]([O:9][CH2:5][C:6]([OH:8])=[O:7])=[C:11]([O:38][CH2:39][C:40]([OH:42])=[O:41])[CH:12]=2)=[O:37])[CH3:19])=[O:36])[CH2:24][CH2:25]1