HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lawesson's reagent → HCID 53810519, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | HCID 53836288 | HCID 53836288 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 53810519 | HCID 53810519 | — |
Reaction Steps
3.4 g of Lawesson's reagent were added to a solution of 1-amino-3-(4-chloro-2-fluoro-5-methoxyiminomethylphenyl)-2,4-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydropyrimidine (3.8 g) in 100 ml of toluene. After refluxing for 12 hours, the solvent was removed and the crude product obtained was purified by chromatography. Yield: 2.2 g; m.p.: 172°-174° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05700805 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-4e3dd8fecf9941a0b5b09d56ebd3304e |
| Source note | uspto-grants-1997_12 |