Hydrochloric Acid → 1-Piperazineacetic acid, 4-(4-pyridinyl)-, hydrochloride (1:2)

HRID 1940514Notes

Reaction equation

HRID 1940514 reaction equation
[ClH:1].Cl.[N:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]([O:18]C)=[O:17])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.Cl>>[ClH:1].[ClH:1].[N:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]([OH:18])=[O:17])[CH2:11][CH2:10]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 67706482HCID 67706482, compound

Product 1

HCID 189185271-Piperazineacetic acid, 4-(4-pyridinyl)-, hydrochloride (1:2)

Procedure

Prepared from methyl [4-(4-pyridyl)-piperazin-1-yl]acetate dihydrochloride and semiconcentrated hydrochloric acid analogously to Example IIb.

Sources & evidence

ORD record
ord-f29db7952c6e41d4a9bdf661c798c7d0
Source dataset
uspto-grants-1997_12
Patent number
US05700801

Reaction notes

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