HCID 21462927, compound → HCID 21462925, compound

Participants

Reaction Steps

A solution of 1 g of 1,2-dihydro-1-(2-methoxybenzyl)-4-(4-methoxyphenyl)-2-oxo-7-nitrobenzofuro[3,2-b]pyridine-3-carboxylic acid, m.p. 245°, prepared analogously to Examples 1 and 2, in 25 ml of methanol is hydrogenated to completion on 1 g of Raney nickel at normal pressure and 20°. The mixture is filtered, the solvent is removed and 7-amino-1,2-dihydro-1-(2-methoxybenzyl)-4-(4-methoxyphenyl)-2-oxobenzofuro[3,2-b]pyridine-3-carboxylic acid, m.p. 268°, is obtained.

Provenance & Evidence