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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1940595Generated: October 30, 2026

HCID 54441057, compound → HCID 67621078, compound

https://huagongshe.com/reaction/1940595

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54441057HCID 54441057—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 67621078HCID 6762107873.5%

Reaction Steps

A solution of 5-nitro-2,3-dihydrobenzofuran-7-yl)-(2-dimethylaminoethyl)carbamic acid tert-butyl ester (D6) (387 mg) in ethanol (50 ml) was hydrogenated over 10% palladium on charcoal for 2 h at atmospheric pressure and room temperature. The catalyst was removed by filtration and the flitrate evaporated under reduced pressure to give the title compound as a brown oil (260 mg, 73%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05700818
Source datasetuspto-grants-1997_12
ORD IDord-f1a53a81635642f79282881b774bbdcd
Source noteuspto-grants-1997_12