HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54441057, compound → HCID 67621078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54441057 | HCID 54441057 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67621078 | HCID 67621078 | 73.5% |
Reaction Steps
A solution of 5-nitro-2,3-dihydrobenzofuran-7-yl)-(2-dimethylaminoethyl)carbamic acid tert-butyl ester (D6) (387 mg) in ethanol (50 ml) was hydrogenated over 10% palladium on charcoal for 2 h at atmospheric pressure and room temperature. The catalyst was removed by filtration and the flitrate evaporated under reduced pressure to give the title compound as a brown oil (260 mg, 73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05700818 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-f1a53a81635642f79282881b774bbdcd |
| Source note | uspto-grants-1997_12 |