o-(Trifluoromethyl)benzaldehyde → HCID 88365257, compound

Participants

Reaction Steps

5-Chloro-2-hydroxy-2'-(trifluoromethyl)benzophenone [prepared from 2-bromo-4-chloro-(2-methyoxyethoxy)methoxybenzene and ortho-(trifluoromethyl)benzaldehyde as the starting materials: melting point, 71°-72° C. (recrystallized from hexane-isopropyl ether)] was reacted by a method similar to Process 1 of Reference Example 25 to yield 6-chloro-2-oxo-4-[2-(trifluoromethyl)phenyl)-2H-1-benzopyran-3-carboxylic acid ethyl ester as an oily substance.

Provenance & Evidence