2-Benzoyl-4,5-dichlorobenzoic acid → HCID 21463235, compound

HRID 1940978Notes

Reaction equation

HRID 1940978 reaction equation
[C:1]([C:9]1[CH:17]=[C:16]([Cl:18])[C:15]([Cl:19])=[CH:14][C:10]=1[C:11]([OH:13])=[O:12])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(C1C=C(C)C(C)=C[C:29]=1[C:30]([OH:32])=[O:31])(=O)C1C=CC=CC=1>>[Cl:18][C:16]1[CH:17]=[C:9]2[C:10](=[CH:14][C:15]=1[Cl:19])[C:11](=[O:12])[O:13][C:29]([C:30]([OH:32])=[O:31])=[C:1]2[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 122052912-Benzoyl-4,5-dichlorobenzoic acidHCID 15214193HCID 15214193, compound

Product 1

HCID 21463235HCID 21463235, compound

Procedure

2-Benzoyl-4,5-dichlorobenzoic acid, in place of 2-benzoyl-4,5-dimethyl-benzoic acid, was reacted and treated in the same manner as in Process 1 of Reference Example 29 to yield 6,7-dichloro-4-phenylisocoumarin-3-carboxylic acid [melting point 243°-244° C. (recrystallized from ethyl acetate-isopropyl ether)]. This compound was reacted and treated in the same manner as in Process 2 of Reference Example 29 to yield the title compound as colorless crystals.

Workup

  1. additiontreated in the same manner as in Process 1 of Reference Example 29

Sources & evidence

ORD record
ord-c8026c4bf2364b7fbd5cfc51b54b02bd
Source dataset
uspto-grants-1997_12
Patent number
US05700810

Reaction notes

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