Sodium Methoxide → HCID 22872542, compound

HRID 1941179Notes

Reaction equation

HRID 1941179 reaction equation
C([O:4][C@H:5]1[C:31](=O)[CH2:30][C@@:29]2([CH3:33])[C@@H:7]([CH2:8][CH2:9][C@@H:10]3[C@@H:28]2[C@H:27]([O:34]C(=O)C)[CH2:26][C@@:25]2([CH3:38])[C@H:11]3[CH2:12][C@@H:13]3[O:18][C@@:17]4([O:24][CH2:23][C@H:21]([CH3:22])[CH2:20][CH2:19]4)[C@@H:15]([CH3:16])[C@@H:14]32)[CH2:6]1)(=O)C.C[O-:40].[Na+]>CO.C1COCC1>[CH3:16][C@@H:15]1[C@:17]2([O:24][CH2:23][C@H:21]([CH3:22])[CH2:20][CH2:19]2)[O:18][C@H:13]2[CH2:12][C@@H:11]3[C@@:25]([CH3:38])([C@@H:14]12)[C:26](=[O:40])[C@@H:27]([OH:34])[C@H:28]1[C@H:10]3[CH2:9][CH2:8][C@@H:7]2[C@:29]1([CH3:33])[CH2:30][CH2:31][C@H:5]([OH:4])[CH2:6]2

Participants

5

Reactant 2

HCID 10942334Sodium MethoxideHCID 54056720HCID 54056720, compound

Product 1

HCID 22872542HCID 22872542, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

(3β,5α,11α,25R)-3,11-di(acetoxy)spirostan-2-one was saponified with sodium methoxide in methanol and THF to give the title compound.

Sources & evidence

ORD record
ord-643ea29afcec427e8cd61c888b471544
Source dataset
uspto-grants-1997_12
Patent number
US05703052

Reaction notes

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