Potassium Carbonate → HCID 21460400, compound

Participants

Reaction Steps

To a mixture of 2-bromo-2-methylpropionylbromid (76 g), K2CO3 (55 g) and dichloromethane (700 ml) was added a solution of 2-benzyloxyethylamine (50 g) in dichloromethane (500 ml) at -10° C. After stirring at room temperature for 1.5 h the mixture was washed with water (500 ml) and dried (MgSO4). Evaporation of the solvents in vacuo afforded N-(2-benzyloxyethyl)-2-bromo-2-methylpropionamide as an oil: 104 g

Provenance & Evidence