Potassium bisulfate → HCID 70276086, compound

Participants

Reaction Steps

1-[1-(4-cyanophenyl)-3-(4-fluorophenyl)-2-propenyl]-1,2,4-triazole 1-[1-(4-cyanophenyl)-3-(4-fluorophenyl)-3-hydroxypropyl]-1,2,4-triazole (100 mg) is heated with potassium hydrogen sulfate (400 mg) on oil bath at 140 ° C. for 2 hours. Methanol is added and the inorganic material is filtered off. Methanol is evaporated to give the product as a mixture of cis and trans isomers.

Provenance & Evidence