(3-Formyl-4-methoxyphenyl)boronic acid → HCID 22106460, compound

HRID 1941505Notes

Reaction equation

HRID 1941505 reaction equation
Br[C:2]1[N:6]([CH2:7][CH:8]2[CH2:10][CH2:9]2)[N:5]=[N:4][N:3]=1.BrC1N=NN(C2CC2)N=1.[CH:20]([C:22]1[CH:23]=[C:24](B(O)O)[CH:25]=[CH:26][C:27]=1[O:28][CH3:29])=[O:21]>>[CH:8]1([CH2:7][N:6]2[C:2]([C:24]3[CH:25]=[CH:26][C:27]([O:28][CH3:29])=[C:22]([CH:23]=3)[CH:20]=[O:21])=[N:3][N:4]=[N:5]2)[CH2:10][CH2:9]1

Participants

4

Reactant 3

HCID 2759225(3-Formyl-4-methoxyphenyl)boronic acidHCID 22106464HCID 22106464, compoundHCID 22106481HCID 22106481, compound

Product 1

HCID 22106460HCID 22106460, compound

Procedure

From a mixture of 5-bromo-1-cyclopropylmethyl-1H-tetrazole with 5-bromo-2-cyclopropyl-2H-tetrazole (1.91 g) and 3-formyl-4-methoxy-phenyl-boronic acid (1.86 g) to give the title compound (657 mg) as a yellow solid. NMR (CDCl3) δ 0.45 (2H,m); 0.70 (2H,m); 1.3 (1H,m); 4.05 (3H,s); 4.3(2H,d); 7.2 (1H,d); 8.0 (1H,m); 8.15 (1H,d); 10.55 (1H,s).

Sources & evidence

ORD record
ord-373c9c3ea3b24c5194b229ecdab32287
Source dataset
uspto-grants-1997_12
Patent number
US05703240

Reaction notes

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