HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 70061333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | HCID 131718659 | HCID 131718659 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 70061333 | HCID 70061333 | — |
Reaction Steps
The title compound can be prepared by treating the title compound of Example 85 with triphenylphosphine and water in THF as described in the literature [N. Knouzi, M. Vaultier, R. Carrie Bull. of Chem. Soc. France, 815 (1985)] which can afford the title compound directly. The product can be purified by reverse phase HPLC using the conditions of Example 1 to afford the title compound. The product can be verified by C NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05703125 |
| Source dataset | uspto-grants-1997_12 |
| ORD ID | ord-a68871fb30fb433186e6ac10a9f1e63a |
| Source note | uspto-grants-1997_12 |