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HRID1941610

反应详情

EQUATION

反应方程式

HRID 1941610 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)NS(N)(=O)=O
HCID10726542

tert-Butyl sulfamoylcarbamate

C5H12N2O4S

结构：CC(=O)S[C@@H]1C[C@H](CO)N(C(=O)OC(C)(C)C)C1
HCID53748200

tert-Butyl (2R,4R)-4-(acetylsulfanyl)-2-(hydroxymethyl)pyrrolidine-1-carboxylate

C12H21NO4S

PRODUCTS

生成物

2
结构：CC(C)(C)OC(=O)NS(N)(=O)=O
HCID10726542

tert-Butyl sulfamoylcarbamate

C5H12N2O4S

结构：CC(=O)S[C@@H]1C[C@H](CN(C(=O)OC(C)(C)C)S(N)(=O)=O)N(C(=O)OC(C)(C)C)C1
HCID54004215

未命名化合物

PROCEDURE

实验过程

N-t-butoxycarbonylsulfamide is prepared in the same manner as in the paragraph (a) of Step A-6 in preparative Example 7-A. (2R,4R)-4-acetylthio-1-t-butoxycarbonylpyrrolidine-2-methanol (i.e., a substrate) is allowed to react with the obtained N-t-butoxycarbonylsulfamide in the similar manner as in paragraph (b) of Step A-6 in Preparative Example 7-A under a condition for Step B-6 shown in Table 2 to give (2R,4R)-4-acetylthio-1-t-butoxycarbonyl-2-(N-t-butoxycarbonyl-N-sulfamoylamino)methylpyrrolidine.