Triphenylphosphine → HCID 73847972, compound

HRID 1941653Notes

Reaction equation

[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([C:10]3[CH:15]=[CH:14][C:13]([C:16](=[N:18][O:19][CH2:20][CH2:21][OH:22])[CH3:17])=[CH:12][CH:11]=3)=[CH:4][C:3]=2[O:2]1.O[C:24]1[CH:56]=[CH:55][C:27]([CH2:28][CH:29]2[S:33][C:32](=[O:34])[N:31]([C:35]([C:48]3[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=3)([C:42]3[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=3)[C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)[C:30]2=[O:54])=[CH:26][CH:25]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.N(C(OCC)=O)=NC(OCC)=O>>[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([C:10]3[CH:11]=[CH:12][C:13]([C:16](=[N:18][O:19][CH2:20][CH2:21][O:22][C:24]4[CH:56]=[CH:55][C:27]([CH2:28][CH:29]5[S:33][C:32](=[O:34])[N:31]([C:35]([C:48]6[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=6)([C:42]6[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=6)[C:36]6[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=6)[C:30]5=[O:54])=[CH:26][CH:25]=4)[CH3:17])=[CH:14][CH:15]=3)=[CH:4][C:3]=2[O:2]1

Participants

Reactant 4

HCID 11776Triphenylphosphine

HCID 220568ethyl N-ethoxycarbonyliminocarbamate

HCID 28181265-(4-Hydroxybenzyl)-3-triphenylmethylthiazolidine-2,4-dione

HCID 54183873HCID 54183873, compound

Product 1

HCID 73847972HCID 73847972, compoundYield 77%

Procedure

Following a procedure similar to that described in Example 1(a), but using 600 mg of 2-[1-(3',4'-methylenedioxybiphenyl-4-yl)ethylideneaminooxy]ethanol (prepared as described in Preparation 30), 907 mg of 5-(4-hydroxybenzyl)-3-tritylthiazolidine-2,4-dione, 550 mg of triphenylphosphine and 365 mg of diethyl azodicarboxylate, 1.12 g of the title compound were obtained as a foam-like solid.

Sources & evidence

ORD record: ord-3bb21ff13b5845ca928628d7e67fbacf
Source dataset: uspto-grants-1997_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05703096

Reaction notes

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