(+)-Fucose → HCID 15559381, compound

HRID 1941748Notes

Reaction equation

HRID 1941748 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH3:11])[OH:10])[OH:8])[OH:6])[OH:4]>[Ni]>[CH2:2]([OH:1])[C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH3:11])[OH:10])[OH:8])[OH:6])[OH:4]

Participants

3

Reactant 1

HCID 94270(+)-Fucose2×

Product 1

HCID 15559381HCID 15559381, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

D-Fucose (6-deoxy D-galactose) was reduced [a composition in total of 500 ml containing D-fucose at 1% and 20 ml of the Raney-nickel catalyst] to produce D-fucitol (6-deoxy D-galactitol). FIG. 57(a) shows HPLC analysis results of D-fucose before reduction and FIG. 57(b) shows HPLC analysis results of 6-deoxy L-galactitol after the reduction. The optical rotation of 6-deoxy L-galactitol was +1.7, and FIG. 58 shows 13C NMR spectrum of 6-deoxy L-galactitol.

Sources & evidence

ORD record
ord-5762e74bbce94cd5bdc2f97717ca399d
Source dataset
uspto-grants-2013_03
Patent number
US08389248B2

Reaction notes

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