huagongshe.com
HRID1941863

反应详情

EQUATION

反应方程式

HRID 1941863 的结构方程式

REACTANTS

反应物

2
结构：CCn1cc(Cl)c(C(=O)O)n1
HCID589820

4-Chloro-1-ethyl-1H-pyrazole-3-carboxylic acid

C6H7ClN2O2

结构：C[C@]1(c2cc(N)ccc2F)N=C(N)OCC1(F)F
HCID58304207

未命名化合物

PRODUCTS

生成物

1
结构：CCn1cc(Cl)c(C(=O)Nc2ccc(F)c([C@@]3(C)N=C(N)OCC3(F)F)c2)n1
HCID53241398

未命名化合物

PROCEDURE

实验过程

The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-1) and 4-chloro-1-ethyl-1H-pyrazole-3-carboxylic acid (CAS512810-20-7) following procedure I yielded the title compound as a white solid. MS (ISP): m/z=416.3 [M+H]+.