HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1941916Generated: November 2, 2026
HCID 59840903, compound → {4-[6-(2-Ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-methanesulfonamide
https://huagongshe.com/reaction/1941916
Participants
| Role | Name | HCID | Charge |
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| Reactant | HCID 59840903 | HCID 59840903 | — |
| Reactant | HCID 86624455 | HCID 86624455 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | {4-[6-(2-Ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-methanesulfonamide | HCID 25100976 | — |
Reaction Steps
A mixture of (4-aminophenyl)methanesulfonyl amide (0.093 g, 0.50 mmol) and 4-chloro-6-(2-ethoxyphenyl)-pyrimidine (0.117 g, 0.50 mmol) in DMFA (3 mL) was stirred at 80° C. till the reaction completion (TLC control). Then the reaction mixture was concentrated in vacuo and the residue recrystallized from isopropanol to give {4-[6-(2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-methanesulfonamide (Compound 6)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08389521B2 |
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| Source dataset | uspto-grants-2013_03 |
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| ORD ID | ord-fca71bb288ed40be917302b47130659e |
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| Source note | uspto-grants-2013_03 |
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