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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1941916Generated: November 2, 2026

HCID 59840903, compound → {4-[6-(2-Ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-methanesulfonamide

https://huagongshe.com/reaction/1941916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59840903HCID 59840903—
ReactantHCID 86624455HCID 86624455—
SolventDimethylformamideHCID 6228—
Product{4-[6-(2-Ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-methanesulfonamideHCID 25100976—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of (4-aminophenyl)methanesulfonyl amide (0.093 g, 0.50 mmol) and 4-chloro-6-(2-ethoxyphenyl)-pyrimidine (0.117 g, 0.50 mmol) in DMFA (3 mL) was stirred at 80° C. till the reaction completion (TLC control). Then the reaction mixture was concentrated in vacuo and the residue recrystallized from isopropanol to give {4-[6-(2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl}-methanesulfonamide (Compound 6)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389521B2
Source datasetuspto-grants-2013_03
ORD IDord-fca71bb288ed40be917302b47130659e
Source noteuspto-grants-2013_03