1-Acetylpiperazine → HCID 50912874, compound

Participants

Reaction Steps

The title compound was prepared in analogy to Example 38 using 6-(6-chloro-imidazo[1,2-b]pyridazin-3-ylmethyl)-7-fluoro-quinoline (Intermediate J, 50 mg, 0.160 mmol) and 1-acetylpiperazine (41.0 mg, 0.320 mmol) (tR 3.17 min (conditions 5), MH+=391, 1H-NMR in DMSO-d6: 8.85 (d, 1H); 8.33 (d, 1H); 7.94 (d, 1H); 7.84 (d, 1H); 7.74 (d, 1H); 7.46 (m, 1H); 7.44 (s, 1H); 7.14 (d, 1H); 4.40 (s, 2H); 3.48 (s, 6H); 3.42 (m, 2H); 2.00 (s, 3H)).

Provenance & Evidence