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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1942185Generated: November 2, 2026

(3-Methyloxetan-3-yl)methanamine → (3-Methyl-oxetan-3-ylmethyl)-(5-phenylethynyl-pyrimidin-2-yl)-amine

https://huagongshe.com/reaction/1942185

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Methyloxetan-3-yl)methanamineHCID 15789550—
Reactant2-Methanesulfonyl-5-phenylethynyl-pyrimidineHCID 57516758—
Product(3-Methyl-oxetan-3-ylmethyl)-(5-phenylethynyl-pyrimidin-2-yl)-amineHCID 52917188—

Reaction Steps

The title compound, white solid, MS: m/e=280.2 (M+H+), can be prepared in accordance with the general method of example 1, step 3 from 2-methanesulfonyl-5-phenylethynyl-pyrimidine (example 1, step 2) and (3-methyloxetan-3-yl)methanamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389536B2
Source datasetuspto-grants-2013_03
ORD IDord-22f223d690914d17b36c561dccdc06dc
Source noteuspto-grants-2013_03