HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → (5-Iodo-imidazo[2,1-b][1,3,4]thiadiazol-2-yl)-propyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | Imidazo[2,1-b][1,3,4]thiadiazol-2-yl-propyl-amine | HCID 58285612 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (5-Iodo-imidazo[2,1-b][1,3,4]thiadiazol-2-yl)-propyl-amine | HCID 58285729 | 36.6% |
Reaction Steps
663 mg of imidazo[2,1-b][1,3,4]thiadiazol-2-yl-propyl-amine were dissolved in 20 ml of acetonitrile. 822 mg of N-iodosuccinimide were added to the solution. The reaction mixture was stirred for 4 h at room temperature. For work-up, the mixture was cooled on ice and filtrated. 410 mg of the desired product were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389554B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-4683d2492c044513aec3142526f604e8 |
| Source note | uspto-grants-2013_03 |